Interaction Checker

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HEP Drug Interaction Checker

Access our comprehensive, user-friendly, free drug interaction charts. Providing clinically useful, reliable, up-to date, evidence-based information

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Site News & Twitter Updates

New comedications for pulmonary hypertension

Four new comedications for the treatment of pulmonary hypertension have been added to the interaction checker. The new comedications liste...

Six new comedications

Six new comedications have been added to the interaction checker. The new drugs (and their therapeutic classes) are listed below.

New DAA combinations

Two new DAA combinations have been added to the interaction charts - glecaprevir/pibrentasvir (Maviret®, Mavyret®) and sofosbuvir/velpatas...

Yellow - a new addition to the interaction classification system

Our interaction classification system has recently been expanded to include a new “yellow” interaction, which now sits between the origina...

Expansion of the interaction classification to include "yellow".

We are have recently expanded our interaction classification to include a new “yellow” classification. In contrast to the existing amber i...

A few new comedications

Three new drugs have been added to the comedication list. Metamizole can be found in th...

New comedications and new therapeutic classes

There have been some additions to the list of comedications and therapeutic classes – 38 new comedications have been added and two new the...

Interactions and Hepatic Impairment

We have reviewed all interactions which mentioned a dose modification was required in hepatic impairment. These interactions were previous...


Epclusa® (velpatasvir/sofosbuvir) has been approved by the FDA and EMA. Interactions with velpatasvir/sofosbuvir are now available on the ...

New HIV combinations added as comedications

Three new HIV antiretroviral fixed-dose combinations have been added to the interaction charts. The new comedications are:

Latest additions to the comedications list

Some new comedications have been added to the interaction charts and are listed below.

Discover Our HEP Mobile Apps

HEP iChart gives easy access to our drug interaction information on mobile devices. Click the links below for further details and to download the HEP iChart app.

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